LOL!!! I received those results with the very same frustration. I had already removed routine PPI from my practice. Should I reimplement it? It also creates a huge mess for medical managers and ICU coordinators.
Perfect. Not to mention the costs. I have spent years trying to rationalize PPI prescriptions. I chose the word “disappointment” in the post but it is an euphemism…
Interesting post. Curiously the pantoprazole group had a greater overall proportion of invasive therapeutic interventions (p<.03) while blood transfusions looked similar (S Table 6). This information would have been useful in the entire ITT sample. They also did not perform an interaction test for enteral nutrition. In the SUP-ICU trial, an interaction was present (p=.024) with increased mortality for the subgroup receiving enteral nutrition + PPI ( https://doi.org/10.1111/aas.14471).
LOL!!! I received those results with the very same frustration. I had already removed routine PPI from my practice. Should I reimplement it? It also creates a huge mess for medical managers and ICU coordinators.
Perfect. Not to mention the costs. I have spent years trying to rationalize PPI prescriptions. I chose the word “disappointment” in the post but it is an euphemism…
Interesting post. Curiously the pantoprazole group had a greater overall proportion of invasive therapeutic interventions (p<.03) while blood transfusions looked similar (S Table 6). This information would have been useful in the entire ITT sample. They also did not perform an interaction test for enteral nutrition. In the SUP-ICU trial, an interaction was present (p=.024) with increased mortality for the subgroup receiving enteral nutrition + PPI ( https://doi.org/10.1111/aas.14471).